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Peter Taylor


Norman Collison Chair of Musculoskeletal Sciences

  • Professor of Clinical Research
  • Director of Clinical Trials Unit

My clinical expertise is in rheumatoid arthritis, ankylosing spondylits and primary inflammatory arthritis. I am head of the clinical trials group at the Kennedy Institute of Rheumatology and director of the Oxford University NIHR musculoskeletal clinical trials unit. My research expertise is in mechanisms sustaining inflammation and clinical trials of new therapies with development of novel outcome measurements for application in assessment of response to therapy as well as providing an early indication of disease modification. These measures include use of ultrasonographic and high-field magnetic resonance imaging technology. I have recently led early phase Ib/IIa clinical trials using such measures as a primary outcome with a view to  providing data that will potentially inform a reliable and  early go/no-go signal and in the former case, inform later phase study design. My research employs targeted therapies as probes of pathogenesis to investigate the in vivo biology of the target in the pathobiology of the disease phenotype under investigation. I have been a principal investigator in numerous international clinical trials of biologic therapies including the earliest seminal trials of anti-TNF and anti-IL-6 receptor therapy, and more recently, chief investigator in a number of international early phase trials of targeted biologic and small molecular therapies.

I studied pre-clinical medical sciences at Gonville and Caius College at the University of Cambridge and obtained my first degree in Physiology. I subsequently studied clinical medicine at the University of Oxford and was awarded a PhD degree from the University of London for studies on pathogenesis of arthritis. Before returning to Oxford, I was Professor of Experimental Rheumatology at the Kennedy Institute of Rheumatology, head of the clinical trials group and Dean of the Charing Cross Hospital campus of Imperial College London. I held an honorary consultant rheumatologist post in Imperial College NHS Healthcare Trust and lead clinician for rheumatology. 

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