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The development of biologic drugs has undoubtedly enhanced the spectrum of treatments available for immune-mediated inflammatory rheumatic diseases such as rheumatoid arthritis. However, despite their clear clinical benifits, use of biologics is often hindered by their high costs. The manufacture and subsequent approval of more cost-effective ‘biosimilar’ versions of these drugs may address this issue and improve patient access. CT-P13 (Remsima®, Inflectra®), a biosimilar of infliximab (Remicade®), has shown comparable efficacy, safety and pharmacokinetics to its originator drug in clinical studies. The articles in this supplement present a scientific update on the development and use of biosimilars in rheumatic disorders, with specific focus on CT-P13. The information discussed highlights the predicted positive clinical and economic impact of biosimilars on the management of rheumatic diseases.

Original publication

DOI

10.1586/1744666X.2015.1090876

Type

Journal article

Journal

Expert Rev Clin Immunol

Publication Date

22/09/2015

Volume

11

Pages

1 - 4